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Gut Wisdom: Understanding the Microbiome for a Happier You

There is more and more research coming every week, it seems, on the importance of the gut microbiome—all of the good little bacteria that help to keep our tummies happy, our brains focused, and our immune system in check.

The researchers at Cleveland and Mayo clinics found that people with cardiovascular disease (CVD) had a very different gut biome than people who did not have CVD.  Part of the difference was the lack of bacterial diversity in the guts of people with CVD. Interestingly, but maybe not surprising, the gut biome of people with CVD was similar to people who have obesity, type 2 diabetes, dyslipidemia, and high blood pressure.

It is estimated that there are 38 TRILLION bacteria in our gut.  If those bacteria are not healthy, that can lead to an increase in inflammation.  The inflammation can leach into our blood streams from the gut and cause changes in the blood vessels leading to arterial plaque and atherosclerosis. 

Since finding this link between an unhealthy microbiome and heart disease, researchers have been looking for a marker to assess heart risk based on gut health.  One marker that is showing a lot of promise is Trimethylanine-N-oxide (TMAO).  People who had the TMAO marker had a 62% increase in having a cardiac event and of those, a 63% increase in risk of death.  This marker has been shown to occur prior to clinically significant changes in lipids or triglycerides. 

Marco Witkowski. Circulation Research. Gut Microbiota and Cardiovascular Disease, Volume: 127, Issue: 4, Pages: 553-570, DOI: (10.1161/CIRCRESAHA.120.316242)

The good news in all this?  A change in diet to support our little bacterial friends decreases the TMAO marker along with a decrease in arterial plaque.  The change in diet should include a mix of prebiotics (which helps to promote the growth of good bacteria) and probiotics (which contain good bacteria to repopulate the gut). 

Probiotics include fermented foods such as:

  • Sauerkraut
  • Kefir
  • Kimchi
  • Yogurt
  • Kombucha
  • Miso
  • Refrigerated pickles
  • Tempeh

Prebiotics are found in most plant based foods.  They have resistant starches that are basically carbohydrates that are not digested in the small intestine and act as bacteria food in the large intestine.  Here are just a few of the many, many options for prebiotics:

  • Asparagus
  • Leeks
  • Sweet potato
  • Flax seed
  • Bananas
  • Garlic
  • Onion
  • Apples
  • Steel cut oats

Other ways to help keep our gut friends healthy are to avoid processed foods, refined carbs, extra sugars and unhealthy fats. You can also lean into these lifestyle changes that will help boost the health of your gut:

  • Exercise 150 minutes weekly of moderate intensity exercise
  • get 7-8 hours of sleep
  • Take time for relaxation and rest, and just breathe
  • Take time to make plans with friends and family whom you enjoy seeing
  • Put away screens and spend time in nature

If you are struggling to stay active, keep on track with a healthy diet and lifestyle, we are here to help. Addressing issues that affect your pelvic health also can help you feel motivated to address other lifestyle factors, and our therapists are integrative providers who will help guide you toward a healthy lifestyle! Click HERE to schedule a free 15 minute consultation with one of our providers now.


Disclaimer: This blog is here for your help. It is the opinion of a Licensed Physical Therapist. If you experience the symptoms addressed you should seek the help of a medical professional who can diagnose and develop a treatment plan that is individualized for you.

Jennifer founded Foundational Concepts, Specialty Physical Therapy in 2013 to focus on pelvic floor physical therapy. She is board certified in women’s health specialty physical therapy and holds a certification in lymphedema therapy. She also has specialty training in assessment and treatment of the temporomandibular joint (TMJ dysfunction) and the integrative systems model. She is an adjunct professor at Rockhurst Physical Therapy program and is clinical faculty for resident education for HCAMidwest gynecology and KU internal resident residents. She has presented at Combined Sections, American Urology Association, and Urology Association of Physician Assistants.

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